Comparison of Photocatalytic Performance of Sr0.9La0.1TiO3 and Sr0.25Ca0.25Na0.25Pr0.25TiO3 Towards Metoprolol and Pindolol Photodegradation

Authors

  • Milana Kudus University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, 21000 Novi Sad, Serbia https://orcid.org/0009-0006-5791-2029
  • Aleksandra Jovanoski Kostić University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, 21000 Novi Sad, Serbia https://orcid.org/0009-0008-5124-8766
  • Maria M. Savanović University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, 21000 Novi Sad, Serbia https://orcid.org/0000-0003-3907-6259
  • Sanja J. Armaković University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, 21000 Novi Sad, Serbia https://orcid.org/0000-0002-3665-1046

DOI:

https://doi.org/10.30544/MMD2

Abstract

The photocatalytic performance of Sr0.9La0.1TiO3 and Sr0.25Ca0.25Na0.25Pr0.25TiO3 perovskite–based catalysts were studied under different radiation types (simulated solar, LED, and UV radiation) for removal of metoprolol and pindolol. The results showed that both materials effectively removed metoprolol and pindolol, with the highest degradation efficiency observed under UV radiation. The degradation efficiency of metoprolol went up to 30% using Sr0.9La0.1TiO3 and Sr0.25Ca0.25Na0.25Pr0.25TiO3 using all mentioned radiation types. Pindolol was degraded more efficiently, using Sr0.9La0.1TiO3 68%, 94%, and 100% of pindolol was degraded after 240 min, under SSI, UV-LED, and UV irradiation. Using Sr0.25Ca0.25Na0.25Pr0.25TiO3, degradation efficiency was 65%, 84%, and 93%, under SSI, UV-LED, and UV irradiation, respectively. The chemical oxygen demand showed that these materials were highly efficient in mineralizing metoprolol and pindolol as well as their intermediates. The mechanisms behind the degradation of metoprolol using perovskite catalysts are complex. Still, ongoing research has indicated that the degradation mechanism occurs through hydroxylation of the aromatic ring or side chains. A similar degradation pathway is suggested for the degradation of pindolol, including opening an indol ring at the nitrogen atom site.

Keywords:

Beta-blockers, Perovskite-type catalysts, UFLC, COD
Supporting Agencies
The authors gratefully acknowledge the financial support of the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (Grant No. ‪451-03-47/2023-01/200125), Association of the International Development of Academic and Scientific Collaboration (www.aidasco.org), The authors also gratefully acknowledge Nikola Kanas, Annu Sharma, and Subramshu S. Bhattacharya, for providing perovskite-type photocatalysts for this research.

References

Armaković, Sanja J., Stevan Armaković, Dragana D. Četojević-Simin, Filip Šibul, and Biljana F. Abramović. "Photocatalytic Degradation of 4-Amino-6-Chlorobenzene-1,3-Disulfonamide Stable Hydrolysis Product of Hydrochlorothiazide: Detection of Intermediates and Their Toxicity." Environmental Pollution 233 (2018): 916-24.

Crossreff

Armaković, Sanja J, Stevan Armaković, Filip Šibul, Dragana D Četojević-Simin, Aleksandra Tubić, and Biljana F Abramović. "Kinetics, Mechanism and Toxicity of Intermediates of Solar Light Induced Photocatalytic Degradation of Pindolol: Experimental and Computational Modeling Approach." Journal of Hazardous Materials 393 (2020): 122490.

Crossreff

Armaković, Sanja J, Aleksandra Jovanoski Kostić, Andrijana Bilić, Maria M Savanović, Nataša Tomić, Aleksandar Kremenović, Maja Šćepanović, Mirjana Grujić-Brojčin, Jovana Ćirković, and Stevan Armaković. "Photocatalytic Activity of the V2O5 Catalyst toward Selected Pharmaceuticals and Their Mixture: Influence of the Molecular Structure on the Efficiency of the Process." Molecules 28 (2023): 655.

Crossreff

Armaković, Sanja J., Maria M. Savanović, and Stevan Armaković. "Titanium Dioxide as the Most Used Photocatalyst for Water Purification: An Overview." Catalysts 13 (2022): 26.

Crossreff

Bilić, Andrijana, Maria M Savanović, Stevan Armakovic, Dragana D Četojević-Simin, Branislava Srđenović Čonić, Nebojša Vlastimir Kladar, and Sanja Josip Armakovic. "Exploring the Influence of Free Radicals on Photolytic Removal of Nadolol from Water: Mechanism of Degradation and Toxicity of Intermediates." Frontiers in Environmental Science 11 (2023): 1119944.

Crossreff

Cleland, John G F, Karina V Bunting, Marcus D Flather, Douglas G Altman, Jane Holmes, Andrew J S Coats, Luis Manzano, et al. "Beta-Blockers for Heart Failure with Reduced, Mid-Range, and Preserved Ejection Fraction: An Individual Patient-Level Analysis of Double-Blind Randomized Trials." European Heart Journal 39 (2018): 26-35.

Crossreff

Criado, S, D Mártire, P Allegretti, J Furlong, S Bertolotti, E La Falce, and N García. "Mass Spectrometric Study of the Photooxidation of the Ophthalmic Drugs Timolol and Pindolol." Die Pharmazie-An International Journal of Pharmaceutical Sciences 58 (2003): 551-53.

Link

Galvis, A., D.A. Zambrano, N.P. van der Steen, and H.J. Gijzen. "Evaluation of Pollution Prevention Options in the Municipal Water Cycle." Journal of Cleaner Production 66 (2014): 599-609.

Crossreff

Hasan, Zubair, and Sung Hwa Jhung. "Removal of Hazardous Organics from Water Using Metal-Organic Frameworks (MOFs): Plausible Mechanisms for Selective Adsorptions." Journal of Hazardous Materials 283 (2015): 329-39.

Crossreff

Ismael, Mohammed, and Michael Wark. "Perovskite-Type LaFeO3: Photoelectrochemical Properties and Photocatalytic Degradation of Organic Pollutants under Visible Light Irradiation." Catalysts 9 (2019): 342.

Crossreff

James, Paul A., Suzanne Oparil, Barry L. Carter, William C. Cushman, Cheryl Dennison-Himmelfarb, Joel Handler, Daniel T. Lackland, et al. "2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)." JAMA 311 5 (2014): 507.

Crossreff

Jovanoski Kostić, Aleksandra, Nikola Kanas, Vladimir Rajić, Annu Sharma, Subramshu S Bhattacharya, Stevan Armaković, Maria M Savanović, and Sanja J Armaković. "Evaluation of Photocatalytic Performance of Nano-Sized Sr0.9La0.1TiO3 and Sr0.25Ca0.25Na0.25Pr0.25TiO3 Ceramic Powders for Water Purification." Nanomaterials (Basel, Switzerland) 12 (2022): 4193.

Crossreff

Kim, Kyoungtea, Eunae Cho, Jae Min Choi, Hwanhee Kim, Ahri Jang, Youngjin Choi, Jae-Hyuk Yu, and Seunho Jung. "Intermolecular Complexation of Low-Molecular-Weight Succinoglycans Directs Solubility Enhancement of Pindolol." Carbohydrate Polymers 106 (2014): 101-8.

Crossreff

Langlois, R, H Ali, and JE Van Lier. "Réaction Du L-Tryptophane Avec Le Radical Peroxyle Du Trichlorocarbone (CCl3OO•) et l'oxygène Singulet (1O2): Formation de Différentes Paires d'hydroperoxydes Isomériques." Journal de Chimie Physique 90 (1993): 985-99.

Crossreff

López, Jessica Guadalupe Piedra, Orlando Haciel González Pichardo, José Alfonso Pinedo Escobar, David Alejandro de Haro del Río, Horacio Inchaurregui Méndez, and Luis Mario González Rodríguez. "Photocatalytic Degradation of Metoprolol in Aqueous Medium Using a TiO2/Natural Zeolite Composite." Fuel 284 (2021): 119030.

Crossreff

Marković, Dragana, and Eleonora Čapelja. "Therapeutic Potential of Psilocybin: A Promising Agent in Treating Major Depressive Disorder." AIDASCO Reviews 1 (2023): 38-45.

Link

Moctezuma, Edgar, Elisa Leyva, Gabriela Palestino, and Hugo de Lasa. "Photocatalytic Degradation of Methyl Parathion: Reaction Pathways and Intermediate Reaction Products." Journal of Photochemistry and Photobiology A: Chemistry 186 (2007): 71-84.

Crossreff

Pinedo, Alfonso, Mariana López, Elisa Leyva, Brenda Zermeño, Benito Serrano, and Edgar Moctezuma. "Photocatalytic Decomposition of Metoprolol and Its Intermediate Organic Reaction Products: Kinetics and Degradation Pathway." International Journal of Chemical Reactor Engineering 14 (2016): 809-20.

Crossreff

Romero, V, N De la Cruz, Renato F Dantas, P Marco, J Giménez, and S Esplugas. "Photocatalytic Treatment of Metoprolol and Propranolol." Catalysis Today 161 (2011): 115-20.

Crossreff

Selvam, Kaliyamoorthy, and Meenakshisundaram Swaminathan. "Photocatalytic Synthesis of 2-Methylquinolines with TiO 2 Wackherr and Home Prepared TiO2 - A Comparative Study." Arabian Journal of Chemistry 10 (2017): 28-34.

Crossreff

Sun, Chunwen, Jose A Alonso, and Juanjuan Bian. "Recent Advances in Perovskite‐type Oxides for Energy Conversion and Storage Applications." Advanced Energy Materials 11 (2021): 2000459.

Crossreff

Uzelac, Maria M., Sanja J. Armaković, Stevan Armaković, Dragana D. Četojević-Simin, Jasmina Agbaba, and Nemanja D. Banić. "The Role of Environmental Waters Ionic Composition and UV-LED Radiation on Photodegradation, Mineralization and Toxicity of Commonly Used β-Blockers." Journal of Molecular Structure 1249 (2022): 131579.

Crossreff

Yang, Hai, Guiying Li, Taicheng An, Yanpeng Gao, and Jiamo Fu. "Photocatalytic Degradation Kinetics and Mechanism of Environmental Pharmaceuticals in Aqueous Suspension of TiO2: A Case of Sulfa Drugs." Catalysis Today 153 (2010): 200-207.

Crossreff

Downloads

Published

31-03-2023

Issue

Vol. 1 No. 1 (2023): Advanced Functional Materials

Section

Advanced Functional Materials

License

Copyright (c) 2023 Sanja J. Armaković, Milana Kudus, Aleksandra Jovanoski Kostić, Maria M. Savanović

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.